Searchable abstracts of presentations at key conferences in endocrinology

ea0013p115 | Comparative | SFEBES2007

Glucocorticoid metabolic pathways in human orbital adipose tissue: a comparison with subcutaneous and omental depots

Onyimba Claire , Bujalska Iwona , Durrani Omar , Abbott Joseph , Khosla Pamela , Moosavi Areeb , Reuser Tristan , Stewart Paul , Tomlinson Jeremy , Walker Elizabeth , Rauz Saaeha

Orbital fat (OF) represents a highly specialised adipose tissue depot that occupies a confined space behind the eyeball known as the orbit. OF fills most of the orbital cavity providing support to the delicate structures that link the eye to the brain, and protects against sight-threatening mechanical and inflammatory trauma. Subcutaneous (SC) and omental (OM) adipose tissues are highly active endocrine organs, regulated in part by glucocorticoids (GCs). The pre-receptor regul...